Asked by: Romaine Elgarresta
asked in category: General Last Updated: 24th June, 2020

Why is the descending loop of Henle thinner than the ascending loop of Henle?

The thin descending loop is highly permeable to water (which is easily transferred to the interstitium) and less permeable to solutes. On the other hand, the thin ascending limb is highly permeable to sodium but impermeable to water.

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In this regard, what is the difference between ascending and descending loop of Henle?

The thin descending limb has low permeability to ions and urea, while being highly permeable to water. The loop has a sharp bend in the renal medulla going from descending to ascending thin limb. The thick ascending limb is impermeable to water, but it is permeable to ions.

Furthermore, why is the ascending loop of Henle thick? Thick ascending limb The medullary ascending limb is largely impermeable to water. Sodium (Na+), potassium (K+) and chloride (Cl) ions are reabsorbed by active transport. This K+ "leak" generates a positive electrochemical potential difference in the lumen.

Herein, what is the function of the descending loop of Henle?

This part of the nephron is called the loop of Henle. Its main function is to reabsorb water and sodium chloride from the filtrate. This conserves water for the organism, producing highly concentrated urine.

What happens to sodium and chloride in the ascending limb of the nephron loop?

The ascending limb (where loop diuretics work) is impermeable to water. NaCl is pumped from the tubule into the interstitium in the ascending limb. The tubular osmolarity decreases and fluid that leaves the loop is hypotonic. The collecting duct is impermeable to water without ADH.

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