Asked by: Neal Uddin
asked in category: General Last Updated: 10th May, 2020

What is the function of Thymopoietin?

LAP2 is an inner nuclear membrane (INM) protein. Thymopoietin is a protein involved in the induction of CD90 in the thymus. TMPO beta is a human homolog of the murine protein LAP2. LAP2 plays a role in the regulation of nuclear architecture by binding lamin B1 and chromosomes.

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Subsequently, one may also ask, what is the function of thymosin?

Thymosin is a hormone secreted from the thymus. Its primary function is to stimulate the production of T cells, which are an important part of the immune system. Thymosin also assists in the development of B cells to plasma cells to produce antibodies.

One may also ask, what causes release of thymosin? Notably, thymosin β4 is secreted from platelets and aids in the formation of crosslinks with fibrin in a time- and calcium-dependent manner in the process of clot formation. This crosslinking is mediated by factor XIIIa, a transglutaminase that is released with thymosin β4 from stimulated platelets.

Furthermore, where is Thymopoietin produced?

Thymopoietin is a 49 amino acid polypeptide which is secreted by epithelial cells of the thymus and affects lymphocyte differentiation.

Which hormone influences the proliferation and maturation of T lymphocytes?

Thymus extracts have been shown to induce selective T cell differentiation of precursor cells from the bone marrow in vitro. The active extract has been identified as a thymic hormone, designated thymopoietin, which has been shown to be synthetized by non-lymphoid, epithelial and dendritic cells [119].

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