Asked by: Karren Sykesasked in category: General Last Updated: 5th February, 2020
What is semi discontinuous DNA replication?
Consequently, what is discontinuous Replication?
discontinuous replication The synthesis of a new strand of a replicating DNA molecule as a series of short fragments that are subsequently joined together. The other strand (leading strand) is synthesized by continuous addition of nucleotides to the growing end, i.e. continuous replication.
One may also ask, why is the lagging strand of DNA discontinuous? Because the lagging strand needs to be replicated in the opposite direction of the way the replication fork is proceeding. And DNA polymerase can proceed only 5' to 3'. Thus, short fragments are produced as the replication fork expands. The lagging strand does so discontinuously in segments called Okazaki fragments.
One may also ask, is the replication of DNA continuous discontinuous or semi discontinuous?
The entire replication process is considered "semi-discontinuous" since one of the new strands is formed continuously and the other is not. During the 1960s, Reiji and Tsuneko Okazaki conducted experiments involving DNA replication in the bacterium Escherichia coli.
Which strand of DNA is replicated exclusively in a discontinuous fashion?
Okazaki fragment On one template strand, DNA polymerase synthesizes new DNA in a direction away from the replication fork movement. Because of this, the new DNA synthesized on that template is made in a discontinuous fashion; each segment is called an Okazaki fragment.