Asked by: Ion Brodmuhler
asked in category: General Last Updated: 6th February, 2020

What is pigment mottling?

Definition: Mottling (spots or blotches with different shades) of the retinal pigment epithelium, i.e., localized or generalized fundal pigment granularity associated with processes at the level of the retinal pigment epithelium.

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Hereof, what causes retinal pigmentation?

Changes in the pigment of the retina can also be a sign of the disease. It develops when abnormal blood vessels grow underneath the retina and leak blood or other fluids, causing scarring and damage to the macula. AMD has three stages, partially defined by the size and number of drusen beneath the retina.

Secondly, why is pigment in the choroid and retina important? Retinal pigment epithelium (RPE) is a layer of dark tissue beneath the photoreceptors. These cells absorb excess light so the photoreceptors can give a clearer signal. They also move nutrients to (and waste from) the photoreceptors to the choroid. The choroid is separate from the RPE.

Subsequently, one may also ask, what is pigment clumping?

Pigment clumping commonly develops in stage 3 IMT2 disease, enlarges in area continuously over time, and is associated with declining visual function.

What are RPE changes in the eye?

The retinal pigment epithelium (RPE) is a pigmented layer of the retina which can be thicker than normal at birth (congenital) or may thicken later in life. Areas of retinal pigment epithelial (RPE) hypertrophy usually do not cause symptoms. They are typically found during routine eye examinations.

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