Asked by: Muhammad El Hassnaoui
asked in category: General Last Updated: 12th May, 2020

What is a tumor specific antigen?

tumor-specific antigen (TOO-mer-speh-SIH-fik AN-tih-jen) A protein or other molecule that is found only on cancer cells and not on normal cells. Tumor-specific antigens can help the body make an immune response against cancer cells.

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In this way, what is tumor associated antigen?

system to fight cancer involved tumour-associated antigens, proteins that are present on the outer surface of tumour cells. Antigens are recognized as “foreign” by circulating immune cells and thereby trigger an immune response.

Likewise, what is the function of tumor associated antigens in the development of cancer? Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful tumor markers in identifying tumor cells with diagnostic tests and are potential candidates for use in cancer therapy. The field of cancer immunology studies such topics.

Thereof, is PSA a tumor associated antigen or a tumor specific antigen?

Tumor-associated antigens in PCa can be proteins that are present on prostate cells and on their malignant counterparts. Examples are prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA), and the cancer/testis antigens (CTAs).

Do cancer cells present antigens?

It is now well established that cancer cells can efficiently present their own antigens and activate immune response leading to their elimination.

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