Asked by: Nihad Morillo
asked in category: General Last Updated: 29th June, 2020

Are there aquaporins in the descending loop of Henle?

In contrast to previous observations, we demonstrate a complete absence of aquaporin-1 along the entire length of descending thin limbs of 90% of short loop nephrons. Conversely, as expected, we identified aquaporin-1 in proximal tubules, descending thin limbs of long loop nephrons, and medullary descending vasa recta.

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Considering this, what is the function of the descending loop of Henle?

This part of the nephron is called the loop of Henle. Its main function is to reabsorb water and sodium chloride from the filtrate. This conserves water for the organism, producing highly concentrated urine.

One may also ask, what is the main substance that moves out of the descending loop of Henle? The three segments of the loops of Henle have different characteristics that enable countercurrent multiplication. The thin descending limb is passively permeable to both water and small solutes such as sodium chloride and urea.

Also to know is, what occurs in the descending limb of the loop of Henle?

The descending loop of Henle receives isotonic (300 mOsm/L) fluid from the proximal convoluted tubule (PCT). The descending portion of the loop of Henle is extremely permeable to water and is less permeable to ions, therefore water is easily reabsorbed here and solutes are not readily reabsorbed.

Where are aquaporins found in the nephron?

Aquaporin-1 (AQP1) is extremely abundant in the proximal tubule and descending thin limb where it appears to be the main site for proximal nephron water reabsorption. It is also present in the descending vasa recta.

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